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Is Protonix Safe ?

USES: treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and pathological hypersecretory diseases

Generic name: Pantoprazole sodium
Brand names: Protonix

Protonix blocks the production of stomach acid. It is prescribed to heal a condition called erosive esophagitis (a severe inflammation of the passage to the stomach) brought on by a persistent backflow of stomach acid (gastroesophageal reflux disease). Later, it may be prescribed to maintain healing and prevent a relapse. It is also used in the treatment of conditions marked by constant overproduction of stomach acid, such as Zollinger-Ellison Syndrome.

Protonix is a member of the "proton pump inhibitor" class of acid blockers, which includes AcipHex, Nexium, Prilosec, and Prevacid.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Protonix.

  • More common side effects may include:
    Abdominal pain, burping, diarrhea, gas, headache, insomnia, nausea, rash, vomiting

Why should Protonix not be prescribed?

If Protonix gives you an allergic reaction, you'll be unable to use it.

Special warnings about Protonix

Protonix has been known to cause several extremely rare--but very serious--side effects, including severe allergic reaction, severe swelling of the face and throat, eye damage, dangerous skin reactions, and inflammation of the pancreas. Seek emergency care immediately if you begin to have difficulty breathing or swallowing, or begin to develop blisters, eruptions, or peeling skin.

If you have a liver condition, make sure the doctor is aware of it. A dosage adjustment may be needed for anyone with serious liver disease.

Protonix has not been tested for safety or effectiveness in children.

Possible food and drug interactions when taking Protonix

If Protonix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Protonix with the following:

Ampicillin (Omnipen)
Iron
Ketoconazole (Nizoral)
Warfarin (Coumadin)

Special information if you are pregnant or breastfeeding

Although no harmful effects during pregnancy are known, there's no definite proof of safety either. Protonix is therefore recommended during pregnancy only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately.

There is a possibility that Protonix may appear in breast milk, causing serious side effects in the nursing infant. If you have to take the drug, you should not plan on breastfeeding.